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Last updated: March 27, 2008
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LIMS & Informatics Highlights from Pittcon 2008

Announcements and Product Introductions by Vendor

The premier conference and exposition on laboratory equipment and chemical analyses in North America, the Pittsburgh Conference (aka Pittcon) was held this year at the Morial Convention Center in New Orleans, LA from March 2-7, 2008.

Once again, there were a number of LIMS and Informatics sessions, short courses, workshops, and tutorials available to feature the latest in LIMS, Informatics, laboratory automation, and laboratory regulations.

More than 1,100 exhibitors showcased their products and services on the Pittcon exhibition floor in 2008. Following is an alphabetical list of the LIMS, Informatics and Lab Data Automation vendors who exhibited at Pittcon 2008. The listing highlights the products the various vendors showcased in their booths, particularly new versions and upgrades.

Accelerated Technology Laboratories (ATL) featured their Sample Master Pro LIMS, Sample Master Result Point, Sample Master Windows PDA Mobile Integration at Pittcon 2007. Based on Microsoft Access, Sample Master LIMS is designed to be used without manuals. Sample Master Result Point is a web-based solution that can submit samples via browser and retrieve results via attached PDF and email the PDF report.

Accessible Information Systems (AIS) exhibited for the first time at Pittcon, highlighting their BTLIMS solution. BTLIMS is a Windows network-based LIMS that enables laboratories to manage complex processes and comply with national and international quality management system requirements. BTLIMS consolidates diverse business processes into a single, compliant platform with a comprehensive data management system. BTLIMS is a paperless and automated program that can handle numerous processes while ultimately providing accurate scientific data.

Advanced Chemistry Development, Inc. showcased their range of software solutions, and launched ACD/AutoChrom for ChemStation and ACD/AutoChrom for Empower 2 Software, the first automated method development system for HPLC, UHPLC, and LC/MS. AutoChrom will help chromatographers reduce their method development time from weeks to days, or less. They also announced an agreement with Agilent Technologies to co-market the new ACD/AutoChrom for ChemStation software that automates method development for Agilent HPLC, Rapid Resolution LC, and LC/MS systems.

Agilent Technologies announced revenue growth of 9% for FY07 and expectations for the same in 1Q08. Their Bioanalytical Business Unit is pursuing several markets, including nanotechnology with a particular focus on nano-materials, from coatings to thin films. To this end, they implemented a new Materials Science Solution Unit (MSSU) in 2007 and introduced a digital microscopy platform to address the growing market. They also announced a push to help fill out the gaps in technologies for workflows, highlighting their purchase of Colloidal Dynamics in 2007 for their Kalabie Electronic Lab Notebook (ELN) solution. The Kalabie ELN is a paperless lab archive with a scalable, integrated platform for cross-team collaboration that interfaces ChemStation to OpenLab. Further efforts to improve workflows were associated with the announcements of five enhancements their flagship gas chromatograph (GC) and GC/mass spectrometer (GC/MS) platforms; enhancements that included an upgrade to Agilent’s Deconvolution Reporting Software for GC/MS used to extract MS signals from complex mixtures.

Ampersand International again featured their Chrom&Spec chromatography data system. Chrom&Spec is a comprehensive software system for data acquisition and processing in GC, HPLC, LC and in other types of chromatography. It provides a complete set of data processing features such as analog-to-digital conversion, data manipulation, noise filtration, integration, peak identification and quantification, as well as report generation. New features highlighted at Pittcon 2008 included algorithms for noise evaluation and filtration, peak approximation, quantification, advanced multi-channel data processing techniques.

Applied Biosystems demonstrated SQL*LIMS 5.0, an enterprise-ready, scalable full Web client application in which the business logic tier is separate from the browser. Extensions from Oracle and Web Services add capabilities behind the scene that connect transparently to other applications. SQL*LIMS is built on a set of specific functional modules that allow users to create a system that meets specific needs without customization or outside assistance. The entire SQL*LIMS family of products are built on the industry standard Oracle RDBMS and provide a scalable Client/Server architecture that allows users to implement from a simple single tier to more complicated three tier designs. In addition, Applied Biosystems together with Labtronics announced the release of Labtronics’ IDM-LimsLink v4.1 that helps labs to eliminate manual data management and ensures the speed, accuracy and security of data recording by electronically transferring valuable instrument data to SQL*LIMS. This new release includes security and audit trail enhancements that assist with deployment of IDM-LimsLink for large numbers of users, across different geographical locations, while still maintaining compliance with data integrity regulations such as 21 CFR Part 11.

Astrix Technology Group discussed their integration and system development services, including their specialty: developing systems that allow scientific organizations to improve their data collection and processing strategies. Their Informatics Division has extensive experience with commercial products and provides numerous services during their evaluation, selection and implementation.

Autoscribe highlighted Matrix Gemini LIMS. Scalable from enterprise implementation to individual laboratories, Matrix LIMS provides exactly the same user experience no matter how the application is accessed, whether via rich client on a LAN, thin client on a WAN or via the Web using a standard browser. Currently they are offering a SAAS version of Matrix that leverages .NET technology as well as a standalone desktop version. Also featured were their Matrix Stability Data Management System for pharmaceutical and food testing; Training Records Manager and Instrument Calibration and Maintenance to assist in record keeping.

Baytek International exhibited their BLISS LIMS solutions that are specially designed for Refining, Petrochemical, Chemical, and Bulk Pharmaceutical laboratories. These included WinBLISS LIMS, WebBLISS LIMS , and BioBLISS LIMS. WinBLISS LIMS offers customization tools and programs, a calculations editor that can store calculations by test type, and web technology functions to query as well as interact with the LIMS. WebBLISS LIMS is an off-the-shelf query and reporting tool specially developed for Baytek’s BLISS LIMS. It is a versatile website where users can easily perform a wide array of functions, from simple searches to complex laboratory searches. BioBLISS LIMS is designed for the bio-fuel industry and brings enhanced functionality to biodiesel labs. Introduced at Pittcon was their new TurboTube sample vial distribution system which networks the autosampler with the lab’s instruments. TurboTube picks up the sample vial from the prep station and delivers it directly into the GC turret and finally disposes of the sample, all under chromatography control.

Bio-Rad Laboratories Informatics Division made several announcements, including a number of new application-specific systems, such as their new plate-based electroporation system, a new microplate adsorbance spectrophotometer, new Bio—Plex disease panels, and regulatory and validation tools for their protein interaction array system. They also highlighted version 3.0 of their KnowItAll Enterprise Server and KnowItAll AnyWare 1.0, a browser-based client. With the KnowItAll Enterprise Server version 3.0, a database may be built on the server and viewed worldwide at all sites of an organization via the KnowItAll Informatics System Windows client or the new KnowItAll AnyWare browser client. KnowItAll AnyWare is a 100% platform-independent, browser-based, and device-independent client that permits the searching and browsing of data stored on a KnowItAll Enterprise Server.

Bruker once again highlighted a mind-blowing array of new systems and solutions, many with stunning new platforms and functions, with President Frank Laukinen stating that this Pittcon is one of their most exciting thanks to a range of new solutions that have “crossed the threshold from the fairly useful to the really useful on several products.” Five new MS products were introduced with enhancements for both small and large molecule analysis for biotech applications, from their ultra FTMS for metabolite imaging to their Next Generation ETD II module that offers significantly better sensitivity for HCT-Ultra high capacity ion traps. A new Smart X2S solution (Crystal-to-Structure) offers the first benchtop X-ray crystallography system for fully automated three-dimensional (3D) chemical structure determination. It is designed for use by chemists who have no special training in crystallography where all the user does is put in the sample. On the software side, they introduced a new NMR Metabolic Profiling Database, now with over 500 compounds, that streamlines metabolite identification and quantification and can be used with their new Compact Avance III NanoBay NMR spectrometer which puts Bruker’s high-performance Avance III NMR spectrometer technology into an exceptionally small footprint.

CambridgeSoft exhibited their life science enterprise solutions for pharmaceutical, biotechnology, chemical companies and academic research organizations. They introduced their new ChemBioOffice Workgroup 2008 suite, which is ideal for smaller organizations or groups that want to organize and search over their inventory, purchase reagents, as well as manipulate and store chemical and biological data in a collaborative fashion. The ChemBioOffice Workgroup applications are compatible with Microsoft SQL Server and accessed through a client side application.

Cerno Bioscience launched MassWorks sCLIPS (Self Calibrated Lineshape Isotope Profile Search), the latest addition to their MassWorks mass spectrometry software suite. Using Cerno’s patented calibration techniques, users of High Mass Accuracy (HMA) instruments can now dramatically improve the results of formula identification and easily obtain higher quality, reproducible data through accurate line-shape calibration. For the first time, sCLIPS now also enables ion trap users to obtain quality formula identification of unknown formula.

ChemWare featured the new Version 10 of their HORIZON Oracle-based LIMS for environmental, water quality, drugs of abuse, chemical demilitarization, and toxicology laboratories, as well as their scalable Web Portal. User-configurable without custom programming, HORIZON LIMS automatically captures electronic records from instruments, scanners and other data sources across the enterprise, integrating the content into compound documents, publishing reports via the web portal, and providing self-service, no-programming query tools and management dashboards for highlighting key operations performance indicators. Version 10 is 100% thin client, runs in Internet Explorer, and provides a sophisticated Business Intelligence interface to management reports. New features include next step prompts, full version control and data traceability that can be evaluated within the context of an operation.

CSols Inc. introduced QAvalid, an Enterprise Compliance Management Solution for Computer Systems Validation (CSV). QAvalid provides a powerful tool to allow companies to achieve regulatory compliance faster and easier. By removing tedious manual tasks for Quality Assurance, QAvalid drives validation costs down and diminishes the risk of non-compliance. In addition to QAvalid, CSols' Professional Services Leaders were on hand to showcase their portfolio of world-class Informatics Professional Services that enable organizations to revolutionize their laboratories and enterprises.

Dionex takes the prize for most press releases this year, introducing a range of new products from ion chromatography solutions to new LC systems and application-specific columns. On the software side, they announced version 2.0 of their DCMSLink plug-in used to provide control of Dionex instruments from Mass Spectrometry software from Thermo Fischer Scientific, (XCalibur), ABI/Sciex (Analyst), and Bruker (HyStar). This upgrade provides many new features, including a unique graphical control interface for Dionex instruments, allowing real-time modification of instrument parameters. They also introduced Service Pack 3 for Release 6.8 of Chromeleon Chromatography Management System that supports Microsoft Windows Vista OS. The new Chromeleon software continues Windows XP support, and adds support for RFIC-ER, the new Dionex eluent regeneration technology that simplifies ion chromatography. New drivers for Agilent 1200 HPLCs, Agilent G1888 Headspace autosamplers, Thermo Accela HPLC systems and Thermo TriPlus autosamplers are also provided.

ELICO Ltd highlighted their software solutions for instrument control, data acquisition with complex analytical capabilities, 21CFR Part 11 compliance, Device Relationship Management (DRM) Solutions, etc., including their SpectraTreats Data Acquisition and Analysis software for UV-VIS, NIR Spectrophotometers.

H&A Scientific is a GMP scientific software development company whose products include PC/Chrom, a multi-channel chromatography package for HPLC, GC, or CE; IntelliFORM, a solution for characterizing batch reactions using UV/Visible spectroscopy, fiber optics, and reaction stations; ChromWave, an Analog-to-Digital Interface Verification package; SLIM, Stability Laboratory Information Manager, for management of drug stability management programs, using Oracle or SQL Server; SLIMStat+, a drug shelf-life projection statistical package; and, IntelliLIMS LIMS for Sample Tracking in the pharmaceutical environment. All were demonstrated or discussed during the conference.

Hanson Research Corporation demonstrated Bill, their Dissolution Data System (DDS) for corporate-wide LIMS interfacing. Developed in an exclusive partnership with Labtronics Inc., Bill creates a seamless digital link between Hanson’s dissolution testing instruments and Labtronics' LimsLink Laboratory Information Management System interface.

iCD Vertriebs GmbH exhibited their LABS/Q LIMS which is available in different iterations targeted to specific applications, including pharmaceutical, process, pollution control, and R&D. Also highlighted were their solutions for synthesis and recipe optimization, method validation, cost control and dissolution tests.

IQC (International Quality Consulting) discussed their laboratory-compliance consulting services. Specialists in regulatory compliance analysis for computerized systems and laboratory equipment, their expertise includes in-depth knowledge of requirements in Europe and North America.

Justice Laboratory Software highlighted their Chrom Perfect CDS solutions, including ChromPerfect LSi for single instrument CDS activities and Chrom Perfect Spirit for client/server multiple instrument CDS requirements.
Laboratory Automation Solutions, a laboratory operations and information management consulting company that serves the analytical testing and research and development industries, showcased their services. The company has implemented LIMS for large and small DoD laboratories, municipal water treatment facilities, commercial environmental laboratories, and industrial testing facilities.

LabTech Holdings highlighted their family of products and services that include UV, HPLC, water recirculating chiller, temperature controllable hotplate, hotblock digester, vacuum pump, hotplate magnetic stirrer, lightwave heater, and LIMS. LabTech's Kuiper-LIMS is a software management system which can collect, analyze, and control laboratory data.
Labtronics Inc featured their new Collect version 6.1 that connects with interface ports such as RS232, parses (extracts) only the required results from the raw data streams, and reports the values directly into Excel, Files, or any Windows application. They also featured their Nexxis qELN, an electronic lab notebook specifically designed to eliminate the paper associated with manual routine procedures in the laboratory.

LabVantage Solutions, Inc. showcased their SAPPHIRE LIMS Suite, a zero footprint and configurable off-the-shelf (COTS) solution consolidating functionality typically found in multiple laboratory systems. With its combination of solutions-oriented modules and multinationalization support, LabVantage’s SAPPHIRE delivers a complete versatile, multi-site and multi-language enterprise backbone for laboratory informatics. They also introduced the new SAPPHIRE Reagents and Standards Management module that provides management, maintenance, and tracking of laboratory consumables. Also featured was the SAPPHIRE Biobanking module for comprehensive and centralized “cradle-to-grave” management of biospecimens.

LabWare unveiled their new Version 3.0 of LabWare Web LIMS that fully embraces the Web paradigm without requiring customers, using the existing Client/Server LIMS product, to make any configuration changes. LabWare's WebLIMS 3.0 delivers the benefits of thin client computing through a zero footprint Web browser client and the ability to run on virtually any Web device. A Visual Workflows engine helps to train new users quickly. In addition, an Enterprise Web application can adapt to specific corporate computing standards. WebLIMS serves as a powerful new presentation layer within the LabWare LIMS product suite and is compatible with customer’s existing installations of LabWare LIMS. In addition, they showcased the new Version 6.0 of their LabWare LIMS, which offers numerous product enhancements as well as a number of new modules.

Moda Technology Partners featured MODA-EM, their mobile data acquisition systems for environmental monitoring (EM); MODA-VIP, a browser-based process intelligence tool that enables the visualization of production-related information within the context of the physical facility; and MODA-FDC (Field Data Capture), a mobile computing platform for collecting, labeling (via barcode) and tracking environmental monitoring samples. MODA-EM addresses the gap between LIMS capabilities and Environmental Monitoring (EM) needs which has long been a problem for analytical labs that struggle to meet the unique challenges of operating in a sterile environment. In addition, they touted their recent agreement with Applied Biosystems to team with XOMA for deployment of SQL*LIMS Micro/EM at XOMA Ltd to automate environmental and utility monitoring and processes at XOMA’s biologics manufacturing facilities in Berkeley, CA.

National Instruments launched their new LabVIEW 8.5 Control Design and Simulation Module, an extension of the LabVIEW graphical system design platform that helps engineers and scientists analyze open-loop model behavior, design closed-loop controllers, simulate systems and create real-time implementations. The latest version of the module introduces new design features such as analytical proportional integral derivative (PID) for improving system closed-loop stability and model predictive control to multivariable systems. The LabVIEW Control Design and Simulation Module also offers expanded support of LabVIEW MathScript with the addition of 18 new .m file functions to simplify such tasks as creating models, defining how models are connected and analyzing system stability.

Novatek International highlighted their Nova-LIMS’ suite of products that can be used independently or as a unit. The Nova-LIMS suite includes: Environmental Monitoring, Stability Studies, Raw Material, Finished Product, Document Management/CAPA/Personnel Training/Audit, Inventory Management, Packaging matériel proof-reading automation, Equipment Calibration and PM.

PerkinElmer, Inc. jumped onto the Green bandwagon in a big way, with the introduction of their new EcoAnalytix Initiative at Pittcon. EcoAnalytix is PerkinElmer’s revolutionary problem-solving initiative that addresses the global imperatives of food and consumer product safety, water quality and sustainable energy development to create a healthy and safe environment. This initiative encompasses comprehensive application-focused solutions with innovative thought leadership and public outreach programs that will bring insights from top scientists, industry experts and government agencies directly to customers. One key component of the initiative is to deliver analyzers that combine the necessary product offerings with the applications, methodologies, standard operating procedures and training required to complete specific analyses in food and consumer product safety, water quality and sustainable energy development. To that end, they not only introduced a number of new instruments and solutions, but all those solutions zeroed in on a green imperative. Including a new LabWorks LIMS, LABWORKS Green, which is a pre-configured LIMS specifically for the biofuels industry. documents. New features such as consumables tracking and Enviroquant Page 3 Edit comparisons were also featured.
Promium demonstrated their Element Datasystem LIMS and their Element FuSioN (Field Sample Network) solution. Designed for field sampling personnel, Element FuSioN downloads sampling and analysis information from laboratories using Promium's Element Datasystem LIMS so samplers can collect the required samples and containers for their project and produce both electronic and hard-copy Chain-of-Custody reports. Element Datasystem is an information management system designed specifically for environmental labs.

Quality Systems International (QSI) featured their new WinLIMS.NET Version 7 ready-to-use, right out of the box web-based solution. Although the database model remains essentially the same as their previous WinLIMS solution, WinLIMS.NET is essentially a brand new product that is radically different than the existing WinLIMS software for three main reasons. First, WinLIMS.NET is a web-based system that was designed using a newer development tool (Microsoft ASP.NET) so the structure of the system is very different. Second, the WinLIMS.NET user interface is more modern and quite different. Third, the interaction with Crystal Reports and Business Objects is also very different. Many new features have been added to the .NET version, including more query tools, the ability to design the dashboard similar to Google Zones functionality, SmartSearch, interactive Excel functionality, and more. WinLIMS .NET takes advantage of Software As A Service (SAAS) technology to reduce the cost of implementing and maintaining a LIMS.

Siemens Automation and Drives (A&D) highlighted their new Sipat software solution to support the application of Process Analytical Technology (PAT) in the pharmaceutical industry. Sipat is scalable and modular and allows a controlled quality growth as the PAT initiative expands. The new software solution serves as a common user-friendly interface for all PAT tools and can be fully integrated into the manufacturing and development architectures. The main feature is the ability to interface with an existing manufacturing architecture, allowing full transparency on quality aspects from unit operation level up to ERP, MES and LIMS. With Sipat pharmaceutical companies are now able to gather process understanding, strive for continuous process improvement, develop processes based on ‘quality by design’ principles and to manufacture ‘right-first-time’. They also highlighted their SIMATIC IT Production Suite. The Production Suite are is designed to provide a range of components or modules to address specific tasks within production operations, providing an end-to-end solution. The various components include the functionality required to update the status of the elements of the plant, update historical records, transform materials, update orders, etc. Components include: SIMATIC IT Material Manager, SIMATIC IT Production Modeler, SIMATIC IT Product Definition Manager, SIMATIC IT Production Order Manager, SIMATIC IT Plant Performance Analyzer, SIMATIC IT Personnel Manager, SIMATIC IT Messaging Manager, SIMATIC IT Predictive Detailed Scheduler, and, of course, SIMATIC IT Unilab LIMS. The SIMATIC IT LIMS is available as a component of Simatic IT or as a stand-alone LIMS that can be easily configured to comply with specific needs of each laboratory – for Quality Control, Central Services and R&D. SIMATIC IT components are engineered and fully harmonized inside the overall architecture and provide detailed functions for handling Manufacturing processes.

STARLIMS Corporation introduced a new SDMS module (Scientific Data Management System) that is integrated into their web-based LIMS. The STARLIMS SDMS is an integrated module that creates a comprehensive platform to manage scientific and laboratory information—consolidating data and documents from the full gamut of laboratory processes. The company claims that the STARLIMS solution is unique in that it integrates LIMS data and SDMS documents into a single web-based platform. Much of the data created in science-centric organizations is unstructured and not typically managed in a consistent fashion, making it difficult to implement systematic procedures necessary to ensure regulatory and legal compliance. The STARLIMS SDMS module enables organizations to capture, parse, search, manage, share and archive scientific documents. Such documents may include research reports, spreadsheets, product specifications, instrument output files and more. The information extracted from these documents is stored in STARLIMS’ unified platform, and managed with the same control as structured LIMS data has been. In addition, the documents are archived and managed in the same platform as the LIMS data, enabling unified searches and eliminating the inefficiencies of multiple data repositories. The company also highlighted their web-based STARLIMS V10 LIMS solution that provides a single unified platform for integrating all lab disciplines. STARLIMS V10 offers enterprise-wide interoperability, no client-side software installations and a short learning curve. At the same time, it provides the advantages typically associated with client/server applications: predictable response times and a full-featured GUI for a rich user experience.

Thermo Electron Corporation featured everything from new instruments to new software, but of particular interest to Pittcon attendees this year were the significant new functionality enhancements to Darwin LIMS, their purpose-built LIMS designed specifically for pharmaceutical QA/QC. Offering environmental monitoring, dissolution, stability management, product and batch management and system interfacing, Thermo Scientific Darwin 3.0 brings new capabilities to pharmaceutical laboratories. Until now, environmental monitoring and LIMS have typically been disparate systems, requiring users to monitor and aggregate data from multiple environmental locations for product and batch traceability. Thermo Scientific Darwin LIMS fully integrates environmental monitoring data into the batch record. Built-in charting tools allow users to visualize each location independent of the samples. This ensures that any failure is apparent at the batch level and allows the laboratory to quickly determine whether the source of the contamination is in the laboratory or the production environment. This embedded functionality enables laboratory managers to react rapidly to non-conforming product before it reaches the consumer. "By linking this data to the LIMS directly, pharmaceutical companies using Darwin can have greater confidence in the quality of their results and, ultimately, in the quality of the product they bring to the consumer,” said Dave Champagne, vice president and general manager for informatics products, Thermo Fisher Scientific. “We believe no other LIMS vendor can offer the scope, breadth and depth our solution delivers.” The new fully validated Web interface of Darwin 3.0 allows for more efficient reporting and sharing of test data across the laboratory. Built on the Microsoft .NET framework, Thermo Scientific Darwin can be easily extended to meet the specific needs of a customer to include dashboard-ready tools for multi-user and multi-site environments. The interface gives immediate information on resource and instrument utilization, so laboratory managers can maximize productivity by optimizing resources.

Velquest demonstrated their SmartLab quality informatics system which integrates with all analytical instruments in the lab. It exchanges data with commercial LIMS and ERP systems with an off-the-shelf offering. This “library-based” capability provides drag-and-drop method automation to execute test methods in SmartLab and point-and-click configured integrations.

Waters Corporation expanded its informatics open architecture operating platform, anchored by the Waters NuGenesis Scientific Data Management System (SDMS), to address predominately manual activities required to perform standard operating procedures (SOPs) for analytical methods or tests. The Waters NuGenesis SDMS Intelligent Procedure Manager is a workflow software package designed to guide a laboratory analysts through routine, comprehensive method SOPs and integrate results with a chromatography data system, such as Waters Empower 2 Chromatography Data Software. From late stage development to final product quality control and lot release, Intelligent Procedure Manager can be equally applied to any lab environment where rigorous adherence to approved test methods and SOPs must be followed, including compliance requirements for cGMP operations. All primary laboratory data and metadata are quickly and easily acquired in electronic form and stored in a secure, 21 CFR Part 11, cGMP-, GLP- compliant database. In addition, Waters highlighted a number of new product introductions, including key extensions to their UPLC product portfolio. These included new applications-specific UPLC-based LCMS systems, new UPLC column chemistries, and pre-column chemistries extensions. A new UPLC-based MS-MS system for food safety analysis was introduced, as well as a new UPLC-based MassTrak AAA solution for the analysis of physiological amino acid analysis in biological fluids. Waters also expanded their MS portfolio with a new SYNAPT MS system that’s a next generation quadrupole orthogonal acceleration, TOF MS platform. Also introduced was a new PATROL UPLC process analyzer, a real-time LC online process analytical technology (PAT) system.